Adjusting to the high altitude of Argentina’s Puna is important because many areas rise well above 3,500 meters. Ascending gradually and spending a night in Salta or Jujuy before reaching higher elevations gives your body more time to adapt. Common symptoms of altitude sickness include headaches and fatigue, while staying hydrated, avoiding alcohol, and limiting rapid elevation gains may help reduce discomfort. Any medication for altitude-related symptoms should only be taken after consulting a qualified medical professional.